Thermo Fisher Scientific RACGAP1 Polyclonal Antibody
Thermo Fisher Scientific의 RACGAP1 Polyclonal Antibody는 인간, 마우스, 랫트에 반응하는 토끼 유래 IgG 항체입니다. Western blot, IHC, ICC/IF, ELISA에 적합하며, 고순도 친화 크로마토그래피로 정제되었습니다. 세포막 및 세포질 단백질 검출에 활용됩니다.
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Thermo Fisher Scientific RACGAP1 Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:100–1:500 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 353–632 of human RGAP1 (NP_0011195761) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.51 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.05% ProClin 300 |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2806463 |
Product Specific Information
Immunogen sequence:
DFVSQTSPMI PSIVVHCVNE IEQRGLTETG LYRISGCDRT VKELKEKFLR VKTVPLLSKV DDIHAICSLL KDFLRNLKEP LLTFRLNRAF MEAAEITDED NSIAAMYQAV GELPQANRDT LAFLMIHLQR VAQSPHTKMD VANLAKVFGP TIVAHAVPNP DPVTMLQDIK RQPKVVERLL SLPLEYWSQF MMVEQENIDP LHVIENSNAF STPQTPDIKV SLLGPVTTPE HQLLKTPSSS SLSQRVRSTL TKNTPRFGSK SKSATNLGRQ GNFFASPMLK
Positive Samples: HeLa, K-562, Jurkat
Cellular Location: Cell membrane, Cleavage furrow, Cytoplasm, Cytoplasmic side, Cytoplasmic vesicle, Midbody, Nucleus, Peripheral membrane protein, Acrosome, Cytoskeleton, Secretory vesicle, Spindle
Target Information
RAC, a small GTPase in the ras family, regulates the formation of membrane ruffles, lamellipodia, and filopodia. It is involved in cytoskeletal actin organization and transformation. The p21 activated kinases (PAKs) are direct targets of active Rac and Cdc42, which induce the assembly of polarized cytoskeletal structures when expressed in fibroblasts. RAC1 and RAC2 are essential components of NADPH oxidase, responsible for generating free radicals.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(원본 이미지 파일: PA5-92378_RACGAP1_Q9H0H5-1_Rabbit.svg, PA5-92378_RACGAP1_Q9H0H5-1_Rabbit_PDP.jpeg)
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