Thermo Fisher Scientific EMAP II Polyclonal Antibody
EMAP II 단백질을 인식하는 Rabbit Polyclonal 항체로, WB, IHC, ELISA에 사용 가능. Human, Mouse, Rat 반응성. Affinity 정제 및 PBS/glycerol buffer로 제공. 세포 내 다양한 소기관에서 발현되는 EMAP II 검출에 적합.
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- PA592381
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- pk
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 25–180 of human AIMP1 (NP_0011358881) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.60 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2806466 |
Product Specific Information
Immunogen sequence:
MANNDAVLKR LEQKGAEADQ IIEYLKQQVS LLKEKAILQA TLREEKKLRV ENAKLKKEIE ELKQELIQAE IQNGVKQIPF PSGTPLHANS MVSENVIQST AVTTVSSGTK EQIKGGTGDE KKAKEKIEKK GEKKEKKQQS IAGSADSKPI DVSRLD
Positive Samples: HL-60, 22RV1, HepG2, HT-29, MCF7, A-549
Cellular Location: Cytoplasm, Cytoplasmic vesicle, Endoplasmic reticulum, Golgi apparatus, Nucleus, Cytosol, Secretory vesicle
Target Information
The protein encoded by this gene is a cytokine specifically induced by apoptosis, involved in the regulation of angiogenesis, inflammation, and wound healing. It sensitizes tumor-associated vasculature to tumor necrosis factor. The precursor protein corresponds to the p43 subunit of the multi-tRNA synthetase complex and modulates aminoacylation activity in normal cells. It also stimulates inflammatory responses after proteolytic cleavage in tumor cells. Multiple transcript variants encoding different isoforms exist, and a pseudogene is located on chromosome 20.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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