Thermo Fisher Scientific CACNA1C Monoclonal Antibody (4D10)
CACNA1C 단백질을 인식하는 mouse monoclonal antibody. Western blot과 ELISA에 사용 가능. Affinity chromatography로 정제된 액상 항체. PBS(pH 7.4) buffer, 보존제 없음. -20°C 보관, 반복 동결 해동 피해야 함.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–5 µg/mL |
| ELISA | 0.03 ng/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 4D10 |
| Immunogen | CACNA1C (NP_000710, 2039–2138 a.a.) partial recombinant protein with GST tag (GST tag MW: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | –20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Protein Sequence:
AVLISEGLGQ FAQDPKFIEV TTQELADACD MTIEEMESAA DNILSGGAPQ SPNGALLPFV NCRDAGQDRA GGEEDAGCVR ARGRPSEEEL QDSRVYVSSL
Target Information
CACNA1C encodes an alpha-1 subunit of a voltage-dependent calcium channel.
Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization.
The alpha-1 subunit consists of 24 transmembrane segments and forms the pore through which ions pass into the cell.
The calcium channel complex includes alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio.
Multiple isoforms exist due to alternative splicing or different encoding genes.
The CACNA1C protein binds to and is inhibited by dihydropyridine.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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