Thermo Fisher Scientific Phospho-BLM (Ser186) Polyclonal Antibody
인간 BLM 단백질의 Ser186 인산화 형태를 인식하는 폴리클로날 항체. Western blot, IHC, ELISA, IP에 사용 가능. 친화 크로마토그래피로 정제된 고순도 제품으로 -20°C에서 안정적 보관 가능. 연구용으로만 사용.
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Thermo Fisher Scientific Phospho-BLM (Ser186) Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (IHC) | Assay-dependent |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Anti-BLM pS186 affinity purified antibody prepared from rabbit serum immunized with a synthetic peptide corresponding to the internal region of human Bloom syndrome protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.66 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | 0.02M potassium phosphate, pH 7.2, with 30% glycerol, 0.15M NaCl |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Store vial at -20°C prior to opening. Aliquot contents and freeze at -20°C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use.
Anti-BLM pS186 is directed against the phosphorylated form of human S186 residue. A BLAST analysis suggests cross-reactivity with human based on 100% sequence homology. Cross-reactivity with BLM pS186 from other sources has not been determined.
Target Information
The protein encoded by this gene belongs to the annexin family of calcium-dependent phospholipid binding proteins, some of which have been implicated in membrane-related events along exocytotic and endocytotic pathways. Annexin 5 functions as a phospholipase A2 and protein kinase C inhibitory protein, with calcium channel activity and potential roles in cellular signal transduction, inflammation, growth, and differentiation. Annexin 5 has also been described as placental anticoagulant protein I, vascular anticoagulant-alpha, endonexin II, lipocortin V, placental protein 4, and anchorin CII. The gene spans 29 kb containing 13 exons and encodes a transcript of approximately 1.6 kb and a protein of about 35 kDa.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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