Thermo Fisher Scientific TAF5 Polyclonal Antibody

Applications and Tested Dilutions

Product Specifications

Product Specific Information

• Recommended shelf life: 1 year from date of receipt
• Application Note: For IHC, epitope retrieval with citrate buffer (pH 6.0) is recommended for FFPE tissue sections.
• Based on 100% sequence identity, this antibody is predicted to react with Mouse.

Target Information

TFIID is a general transcription factor that initiates preinitiation complex assembly through direct interaction with the TATA promoter element. It is a multisubunit complex consisting of a small TATA-binding polypeptide and other TATA-binding protein (TBP)-associated factors (TAFs).
Although native TFIID can mediate both activator-independent (basal) and activator-dependent transcription in reconstituted systems, TBP can mediate only basal transcription.
TAF II p100 (also known as TAF5 or TAFII100) is the third largest subunit of human TFIID. It contains six WD40 repeats at the C-terminus and an N-terminus capable of forming a flexible dimer.
TAF II p100 plays an important role in forming the scaffold crucial for the assembly of the TFIID complex and may also be involved in the stabilization of TAF interactions.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.