Thermo Fisher Scientific LGR7 Polyclonal Antibody
Thermo Fisher Scientific의 LGR7 Polyclonal Antibody는 Human과 Mouse 시료에 반응하며 Western blot, IHC(P), IHC(F) 등에 사용 가능합니다. Rabbit IgG 기반의 액상 비결합 항체로, RXFP1 단백질의 694-732 아미노산 범위를 면역원으로 사용합니다. 연구용으로만 사용됩니다.
- 카탈로그번호
- PA523227
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: Assay-Dependent
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:100
Immunohistochemistry (Frozen) (IHC (F))
- Tested Dilution: Assay-Dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Within the range of amino acids 694–732 of human RXFP1 protein were used as the immunogen for this antibody. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | Not Determined |
| Storage Buffer | Whole serum with 50% glycerol |
| Contains | 0.025% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2540752 |
Target Information
LGR7 is a low-density lipoprotein receptor composed of 757 amino acids, belonging to the G-protein coupled receptor 1 family with rhodopsin-like receptor activity.
It contains seven transmembrane regions, a cysteine-rich motif, 10 LRR domains, and 5 N-glycosylation sites at the N terminus.
Research indicates that LGR7 acts as a receptor for relaxins (RLN1 and RLN2), which stimulate adenylate cyclase activation, substrate adhesion, and chemo migratory capacity of mononuclear leukocytes.
LGR7 is critical for mediating these biological responses through RNA interference lentiviral short hairpin constructs.
It is widely expressed in 86% of 15 primary EC tissue samples, including brain, kidney, testis, and endometrium.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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