Thermo Fisher Scientific VANGL1 Polyclonal Antibody
VANGL1 단백질을 인식하는 Rabbit Polyclonal 항체로 Western blot에 적합. 합성 펩타이드 면역원으로 제작되었으며, 비결합형 액상 형태로 제공. 단기 4°C, 장기 -20°C 보관 권장. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 3.0–5 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide (376 QAEEQQKAPGEVMDPREA 394) of Vang-like 1 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2540754 |
Target Information
Vang-like 1 protein is a novel human homologue of Drosophila Van Gogh/Strabismus. The Vang-like 1 gene consists of at least 7 exons and encodes a protein with four transmembrane domains and a C-terminal Ser/Thr-X-Val motif. Studies show that the expression of this protein is significantly up-regulated in gastric cancer cell lines (MKN28, MKN74) and pancreatic cancer cell lines (BxPC-3, PSN-1, Hs766T). The protein may act as an effector mediating the intestinal trefoil factor (ITF) healing response of the intestinal mucosa. It also serves as a diagnostic marker for hepatocellular carcinoma and as a potential molecular target for novel therapeutic drug development. Additionally, its pathological role has been identified in neural tube defects (NTD). The human Vang-like 1 gene maps to chromosome 1p11–p13.1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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