Thermo Fisher Scientific FCAR Recombinant Rabbit Monoclonal Antibody (002)
Human CD89/FCAR을 인식하는 recombinant rabbit monoclonal antibody. ELISA에 적합하며, 높은 특이성과 재현성을 제공. 보존제가 없는 형태로 제공되며, 단백질 A로 정제됨. 연구용으로만 사용 가능.
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Applications
- ELISA (ELISA): 1:250–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 002 |
| Immunogen | Recombinant Human CD89/FCAR Protein (Met1–Asn227) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage buffer | PBS |
| Contains | No preservative |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2786140 |
Product Specific Information
This product is preservative-free. It is recommended to add sodium azide (final concentration 0.05%–0.1%) to prevent contamination.
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems by cloning specific antibody DNA sequences from immunoreactive rabbits. Individual clones are screened to select optimal candidates for production.
Advantages include:
- High specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulation
- Broad immunoreactivity due to the large rabbit immune repertoire
This antibody specifically recognizes Human CD89/FCAR.
Target Information
The FCAR gene encodes a receptor for the Fc region of IgA and belongs to the immunoglobulin gene superfamily.
This transmembrane glycoprotein is expressed on myeloid lineage cells (neutrophils, monocytes, macrophages, eosinophils) and mediates immune responses to pathogens.
It interacts with IgA-opsonized targets, triggering defense mechanisms such as:
- Phagocytosis
- Antibody-dependent cell-mediated cytotoxicity
- Release of inflammatory mediators
Multiple alternatively spliced transcript variants encoding different isoforms have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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