Thermo Fisher Scientific Phospho-VEGF Receptor 2 (Tyr951) Polyclonal Antibody
Phospho-VEGF Receptor 2 (Tyr951) 항체로 인간 및 마우스 시료에 반응. IHC 및 ICC/IF에 적합하며, 고순도(>95%) 항원 친화 크로마토그래피 정제 제품. 1 mg/mL 농도의 액상 형태로 제공되며, 4°C 단기 보관 및 -20°C 장기 보관 권장.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic phosphopeptide derived from human VEGFR2 around the phosphorylation site of Tyrosine 951 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2553669 |
Product Specific Information
- This antibody detects endogenous protein at a molecular weight of 150 and 210 kDa.
- Purity is >95% by SDS-PAGE.
Target Information
KDR (FLK1, VEGFR2) is a type III receptor tyrosine kinase that binds vascular endothelial growth factor (VEGF) with high affinity. It is expressed early in development by endothelial cell precursors. FLK1 (VEGF Receptor 2) encodes one of the two receptors of VEGF, also known as kinase insert domain receptor.
The signaling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin αVβ3, and T-cell protein tyrosine phosphatase.
Mutations of FLK1 (VEGF Receptor 2) are implicated in infantile capillary hemangiomas.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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