Thermo Fisher Scientific CHCHD3 Monoclonal Antibody (OTI7G4), TrueMAB
인간 CHCHD3 단백질(aa 2-227)을 인식하는 Mouse IgG1 단클론 항체. Western blot 및 IHC(P) 검증 완료. 동결건조 형태, PBS 버퍼와 trehalose 포함. 미토콘드리아 내막 구조 유지 연구에 적합.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: Assay-Dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI7G4 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 2–227 of human CHCHD3 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step.
Recommended: Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL (Product #89882).
Target Information
CHCHD3 is a component of the MICOS complex, a large mitochondrial inner membrane protein complex crucial for maintaining crista junctions, inner membrane architecture, and contact sites with the outer membrane.
It also functions as a transcription factor that binds to the BAG1 promoter, repressing BAG1 transcription.
CHCHD3 is essential for MICOS complex stability and mitochondrial cristae morphology.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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- CF803455_CHCHD3_Q9NX63-1_House_mouse.svg
- CF803455_CHCHD3_Q9NX63-1_House_mouse_PDP.jpeg
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