Thermo Fisher Scientific S6 Monoclonal Antibody (C.896.4)
S6 단백질을 표적으로 하는 Thermo Fisher Scientific의 C.896.4 단일클론 항체로, Western blot, IHC, ICC, Flow cytometry 등에 적합. 인간, 생쥐 등 다양한 종에 반응하며, 액상 형태로 제공. 연구용 단백질 합성 및 세포 성장 조절 연구에 활용 가능.
- 판매단위
- pk
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000 | View 2 publications |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:125 | - |
| Immunocytochemistry (ICC/IF) | 1:100 | View 2 publications |
| Flow Cytometry (Flow) | 1:50–1:200 | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Fruit fly, Human, Mouse, Non-human primate, Rat |
| Published Species | Human, Mouse |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | C.896.4 |
| Immunogen | Recombinant fusion protein corresponding to full-length human S6 ribosomal protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 5 µg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | 0.01M HEPES, pH 7.5, with 0.15M NaCl, 100 µg/mL BSA, 50% glycerol |
| Contains | <0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_10999800 |
Product Specific Information
It is not recommended to aliquot this antibody.
Target Information
Ribosomes are organelles that catalyze protein synthesis and consist of a small 40S subunit and a large 60S subunit. These subunits include 4 RNA species and approximately 80 distinct proteins. The S6 gene encodes a cytoplasmic ribosomal protein that is part of the 40S subunit and belongs to the S6E family. It is a major substrate of ribosomal protein kinases, with phosphorylation occurring on five C-terminal serine residues. Phosphorylation is induced by stimuli such as growth factors and mitogens, while dephosphorylation occurs during growth arrest. This protein may regulate cell growth and proliferation through selective translation of specific mRNA classes. Multiple processed pseudogenes of this gene are dispersed throughout the genome.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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