Thermo Fisher Scientific Jagged1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:200-1:500

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human JAG1. Recombinant protein control fragment (Product #RP-93722). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Jagged1,uniProtId:P78504-1,ncbiNodeId:9606,antigenRange:1093-1217,antigenLength:1218,antigenImageFileName:PA5-82765_Jagged1_P78504-1_Rabbit.svg,antigenImageFileNamePDP:PA5-82765_Jagged1_P78504-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.3 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2789921

Product Specific Information

Immunogen sequence: LRKRRKPGSH THSASEDNTT NNVREQLNQI KNPIEKHGAN TVPIKDYENK NSKMSKIRTH NSEVEEDDMD KHQQKARFAK QPAYTLVDRE EKPPNGTPTK HPNWTNKQDN RDLESAQSLN RMEYI

Target Information

The jagged 1 protein encoded by JAG1 is the human homolog of the Drosophilia jagged protein. Human jagged 1 is the ligand for the receptor notch 1, the latter a human homolog of the Drosophilia jagged receptor notch. Mutations that alter the jagged 1 protein cause Alagille syndrome. Jagged 1 signalling through notch 1 has also been shown to play a role in hematopoiesis.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.