Thermo Fisher Scientific ARTS Polyclonal Antibody
Human SEPT4 단백질을 인식하는 Rabbit Polyclonal Antibody. Western blot 및 IHC(P) 검증 완료. 항원 친화 크로마토그래피로 정제된 액상 항체로, PBS(glycerol 포함)에 보관. 세포사멸 관련 연구용으로 적합.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:20–1:50 | – |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human SEPT4. Recombinant protein control fragment (Product # RP-93189) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2789923 |
Product Specific Information
Immunogen sequence:
YDDDLEFRPP SRPQSSDNQQ YFCAPAPLSP SARPRSPWGK LDPYDSSEDD KEYVGFATLP NQVHRKS
Target Information
Apoptosis is related to many diseases and developmental processes. Mitochondrial proteins such as cytochrome c, Apaf-1, and AIF play important roles in apoptosis.
A novel mitochondrial septin-like protein, designated ARTS, was identified for its role in the TGF-beta signaling pathway related to apoptosis.
ARTS, encoded by the human septin H5/PNUTL2/CDCrel2b gene, localizes to mitochondria and translocates to the nucleus during apoptosis.
It is expressed in many tissues and enhances cell death induced by TGF-beta and, to a lesser extent, by TNF-α and Fas ligand.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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