Thermo Fisher Scientific PHF6 Polyclonal Antibody
PHF6 단백질을 인식하는 Rabbit Polyclonal 항체로 Western Blot, IHC(P), ICC/IF에 적합합니다. Human 시료에 반응하며, 항원 친화 크로마토그래피로 정제되었습니다. PBS 기반 용액 형태로 제공되며, 장기 보관 시 -20°C에서 안정적으로 유지됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human PHF6. Recombinant protein control fragment (Product #RP-92012). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2645498 |
Product Specific Information
Immunogen sequence:
MSSSVEQKKG PTRQRKCGFC KSNRDKECGQ LLISENQKVA AHHKCMLFSS ALVSSHSDNE SLGGFSIEDV QKEIKRGTKL MCSLCHCPGA TIGCDVKTCH RTYHYHCALH DK
Highest antigen sequence identity to the following orthologs:
- Mouse: 98%
- Rat: 98%
Target Information
The PHF6 gene belongs to the plant homeodomain (PHD)-like finger (PHF) family. It encodes a protein with two PHD-type zinc finger domains, suggesting a role in transcriptional regulation and nucleolar localization. Mutations in this gene are associated with Borjeson-Forssman-Lehmann syndrome (BFLS), characterized by intellectual disability, epilepsy, hypogonadism, hypometabolism, obesity, and distinct facial features. Several splice variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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