Thermo Fisher Scientific Cystatin A Polyclonal Antibody
Human Cystatin A를 인식하는 Rabbit Polyclonal Antibody로, WB, IHC, ICC/IF에 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, PBS/glycerol buffer에 보관. 피부 및 암 연구 등에서 Cystatin A 단백질 분석에 적합.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:500 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human Cystatin A. Recombinant protein control fragment (Product #RP-93681). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2640342 |
Product Specific Information
Immunogen sequence:
IPGGLSEAKP ATPEIQEIVD KVKPQLEEKT NETYGKLEAV QYKTQVVAGT NYYIKVRAGD NKYMHLKVFK SLPGQNEDLV
Highest antigen sequence identity to orthologs:
- Mouse: 60%
- Rat: 65%
Target Information
The cystatin superfamily includes proteins with multiple cystatin-like sequences. Some act as cysteine protease inhibitors, while others have lost this function.
This gene encodes a stefin that inhibits cysteine proteases such as papain and cathepsins B, H, and L.
It is a precursor protein of the cornified cell envelope in keratinocytes, contributing to epidermal development and maintenance.
Stefins are proposed as potential prognostic and diagnostic biomarkers for cancer.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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