Thermo Fisher Scientific NBPF15 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:200-1:500

-

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human NBPF15. Recombinant protein control fragment (Product #RP-108172).

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.2 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2790797

Product Specific Information

Immunogen sequence: SGCLELTDSC QPYRSAFYVL EQQRV

Target Information

NBPF15 (NBPF Member 15), located on 1q21.1, is a Protein Coding gene. This gene is a member of the neuroblastoma breakpoint family (NBPF) which consists of dozens of recently duplicated genes primarily located in segmental duplications on human chromosome 1. This gene family contains numerous pseudogenes. Human NBPF15 encodes a 670 AA protein consisting of six clades of Olduvai domains. The entanglements between the mosaic disorder-ordered segments in the NBPF15 N terminus have triggered the multiple types of aggregates and phase transition of NBPF15 proteins, which could be associated with Olduvai-related cognitive dysfunction diseases. Diseases associated with NBPF15 include Neuroblastoma and Hydrolethalus Syndrome 1. An important paralog of this gene is NBPF14.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.