Thermo Fisher Scientific CD45 Monoclonal Antibody (K252.1E4), FITC
돼지 CD45 항원을 인식하는 단클론 항체로, FITC 형광 표지되어 유세포분석에 적합. 모든 CD45 아이소폼에 반응하며, 단기 4°C 및 장기 -20°C 보관 가능. 연구용으로만 사용.
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Thermo Fisher Scientific CD45 Monoclonal Antibody (K252.1E4), FITC
Applications
- Flow Cytometry (Flow)
Tested Dilution
- Neat
Publications
- [References not provided]
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Pig |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | K252.1E4 |
| Immunogen | Porcine Peripheral Blood lymphocytes |
| Conjugate | FITC (Fluorescein) |
| Excitation / Emission Max | 498 / 517 nm |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS with 1% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Store in the dark. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2745346 |
Additional Formats
Product Specific Information
Mouse anti-Pig CD45, clone K252.1E4 recognizes an epitope common to all porcine CD45 isoforms (Schnitzlein et al. 1998).
Target Information
CD45 (LCA, leukocyte common antigen) is a receptor-type protein tyrosine phosphatase (PTP) expressed in all nucleated hematopoietic cells, comprising about 10% of lymphocyte surface proteins. It is absent in non-hematopoietic tissues and cell lines.
CD45 glycoprotein plays a critical role in lymphocyte development and antigen signaling, regulating Src-family kinases and JAK kinases.
It exists in multiple isoforms due to alternative splicing, differing in extracellular domains but sharing identical transmembrane and cytoplasmic regions.
CD45 is essential for T- and B-cell receptor signaling, cytokine signaling regulation, and integrin-mediated survival pathways. It also influences apoptosis and various immune functions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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