
Thermo Fisher Scientific GCKR Polyclonal Antibody
GCKR 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot에 적합합니다. Human, Mouse, Rat 시료에 반응하며, Affinity chromatography로 정제되었습니다. PBS와 50% glycerol에 보관되며 -20°C에서 안정적으로 저장됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human GCKR (Accession Q14397), corresponding to amino acid residues G207–S257 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2899911 |
Product Specific Information
Antibody detects endogenous levels of total GCKR.
Target Information
This gene encodes a protein belonging to the GCKR subfamily of the SIS (Sugar ISomerase) family of proteins. The gene product is a regulatory protein that inhibits glucokinase in liver and pancreatic islet cells by binding non-covalently to form an inactive complex with the enzyme. This gene is considered a susceptibility gene candidate for a form of maturity-onset diabetes of the young (MODY).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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