Thermo Fisher Scientific GDNF Polyclonal Antibody
GDNF 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot에 적합합니다. 인간 및 생쥐 시료에 반응하며, 고순도의 Affinity chromatography로 정제되었습니다. PBS와 50% glycerol에 보관되며, -20°C에서 안정적으로 저장 가능합니다.
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Applications
- Western Blot (WB): 1:1,000–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human GDNF (Accession P39905), corresponding to amino acid residues P29–P79 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2899915 |
Product Specific Information
Antibody detects endogenous levels of total GDNF.
Target Information
GDNF (Glial cell line-derived neurotrophic factor) is a glycosylated, disulfide-bonded homodimer molecule. It was first discovered as a potent survival factor for midbrain dopaminergic neurons and has been shown to rescue these neurons in animal models of Parkinson’s disease. GDNF is approximately 100 times more efficient as a survival factor for spinal motor neurons compared to neurotrophins. It promotes survival and morphological differentiation of dopaminergic neurons and enhances their high-affinity dopamine uptake.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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