Thermo Fisher Scientific GDF11 Polyclonal Antibody
GDF11 단백질을 특이적으로 인식하는 Rabbit Polyclonal 항체. Western blot 및 Immunocytochemistry에 적합. 인간 및 생쥐 시료에 반응. 친화 크로마토그래피로 정제된 액상 형태. 연구용으로만 사용 가능.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:3,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human GDF11 (Accession O95390), corresponding to amino acid residues L274–A324 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2899913 |
Product Specific Information
This antibody detects endogenous levels of total GDF11.
Target Information
GDF11 is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. These proteins are characterized by a polybasic proteolytic processing site that is cleaved to produce a mature protein containing seven conserved cysteine residues. Members of this family regulate cell growth and differentiation in both embryonic and adult tissues. Studies in mice and Xenopus suggest that GDF11 is involved in mesodermal formation and neurogenesis during embryonic development.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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