
Thermo Fisher Scientific Phospho-EPS15 (Tyr849) Polyclonal Antibody
Phospho-EPS15 (Tyr849) 폴리클로날 항체로 인간, 마우스, 랫트 시료에서 사용 가능. WB, IHC, ICC/IF 등 다양한 응용에 적합. EPS15의 Tyr849 인산화 상태를 특이적으로 검출. 고순도 정제 및 안정한 PBS/glycerol 저장용액 제공.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human EPS15 (Accession P42566), corresponding to amino acid residues around phosphorylated Tyr849 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2902999 |
Product Specific Information
Antibody detects endogenous levels of EPS15 only when phosphorylated at Tyrosine 849.
Target Information
EPS15 is a ubiquitously expressed protein involved in cell growth regulation and may play a role in mitogenic signaling and cell proliferation control. Phosphorylation at Tyrosine 849 upon DNA damage is linked to EGFR internalization. Chromosomal aberrations involving EPS15 are associated with acute leukemias, resulting in abnormal activator protein formation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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