Thermo Fisher Scientific Dysferlin Polyclonal Antibody
Dysferlin 단백질을 인식하는 Rabbit Polyclonal Antibody로, 인간·생쥐·쥐 시료에 반응합니다. Western blot, IHC, ICC/IF에 사용 가능하며, Affinity chromatography로 정제된 액상 형태입니다. 근위축증 연구용으로 적합한 연구 전용 항체입니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human DYSF (Accession O75923), corresponding to amino acid residues A1993–F2043 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2903000 |
Product Specific Information
This antibody detects endogenous levels of total Dysferlin.
Target Information
Dysferlin is the protein product of the 2p13 gene that is defective in patients with Limb-Girdle Muscular Dystrophy type 2B (LGMD2B) and Miyoshi Myopathy (MM). Dysferlin is normally localized to the muscle plasma membrane. In patients with LGMD2B and MM, immunoreactivity to dysferlin is severely reduced or lost, depending on the type of mutation. This antibody is used for the characterization of LGMD2B and MM.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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