Thermo Fisher Scientific EXD1 Monoclonal Antibody (OTI1A2), TrueMAB
EXD1 단백질을 인식하는 마우스 단클론 항체로, Western blot, ICC/IF, Flow cytometry에 사용 가능. 인간 시료 반응성. 동결건조 형태로 제공되며, 재구성 후 1 mg/mL 농도로 사용. 연구용으로만 사용.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1A2 |
| Immunogen | Full length human recombinant protein of human EXD1 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (recommended: Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
EXD1 is an RNA-binding component of the PET complex, a multiprotein complex required for the processing of piRNAs during spermatogenesis.
The piRNA metabolic process represses transposable elements during meiosis by forming complexes with Piwi proteins, governing methylation and repression of transposable elements to maintain germline integrity.
Within the PET complex, EXD1 likely acts as an RNA adapter and is an inactive exonuclease.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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