Thermo Fisher Scientific Human NANOS3 Synthetic Peptide
Human NANOS3 단백질의 C-말단 16개 아미노산 서열에 해당하는 합성 펩타이드로, 항체 PA5-20537의 블로킹 펩타이드로 사용 가능. 정제된 액상 형태이며 PBS(pH 7.2)와 0.1% BSA, 0.02% sodium azide를 포함. 연구용으로만 사용.
- 카탈로그번호
- PEP0657
- 카테고리
- Protein
- 판매단위
- pk
카탈로그
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Applications
Control (Ctrl)
- Assay-dependent
Blocking Assay (BLOCK)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
Product Specific Information
This peptide corresponds to 16 amino acids near the carboxy terminus of human Nanos3.
PEP-0657 can be used as a blocking peptide with polyclonal antibody PA5-20537.
Target Information
Nanos is a zinc-finger containing, RNA-binding protein involved in germ cell development in both invertebrates and vertebrates.
In Drosophila, Nanos represses apoptosis during development to ensure proper germ-line formation.
In mammals, Nanos2 and Nanos3 are essential for germ cell development, while Nanos1 is dispensable.
Nanos2-deficient primordial germ cells (PGCs) die only in male gonads, whereas Nanos3-deficient PGCs are lost during migration in both sexes.
Distinct expression patterns of Nanos2 and Nanos3 during embryogenesis suggest non-redundant functions, though Nanos2 expression can partially compensate for Nanos3 deficiency.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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