Thermo Fisher Scientific Pan Ras Recombinant Rabbit Monoclonal Antibody (SA39-05)
Pan Ras 단백질을 인식하는 재조합 토끼 단클론 항체로, Western blot 및 Flow cytometry에 적합합니다. 높은 특이성과 민감도를 제공하며, 로트 간 일관성이 우수합니다. 동물 유래 성분이 없는 포뮬레이션으로 연구용에 최적화되어 있습니다.
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- MA531963
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Thermo Fisher Scientific Pan Ras Recombinant Rabbit Monoclonal Antibody (SA39-05)
Applications and Tested Dilutions
- Western Blot (WB): 1:500–1:2,000
- Flow Cytometry (Flow): 1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat, Zebrafish |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | SA39-05 |
| Immunogen | Synthetic peptide within Human Ras aa 7–56 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | TBS, pH 7.4, with 40% Glycerol, 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2809257 |
Product Specific Information
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems developed by cloning antibody DNA sequences from immunoreactive rabbits. Individual clones are screened to select optimal candidates for production.
Advantages include:
- Enhanced specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulations
- Broader immunoreactivity due to rabbit immune repertoire
Target Information
The Ras gene family encodes small GTP-binding proteins involved in signal transduction. These proteins cycle between GTP- and GDP-bound states and possess intrinsic GTPase activity. Ras proteins regulate membrane localization through palmitoylation cycles.
Mutations in Ras genes are associated with Costello syndrome and various cancers, including bladder, thyroid, and oral squamous cell carcinoma. Multiple transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
- MA5-31963_Pan_Ras_P01111-1_Rabbit.svg
- MA5-31963_Pan_Ras_P01116-1_Rabbit.svg
- MA5-31963_Pan_Ras_P01112-1_Rabbit.svg
- MA5-31963_Pan_Ras_P01111-1_Rabbit_PDP.jpeg
- MA5-31963_Pan_Ras_P01116-1_Rabbit_PDP.jpeg
- MA5-31963_Pan_Ras_P01112-1_Rabbit_PDP.jpeg
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