Thermo Fisher Scientific IL-4 Polyclonal Antibody
고양이 IL-4 단백질을 인식하는 Thermo Fisher Scientific의 염소 유래 다클론 항체. Western blot 및 중화 실험에 적합하며, 항원 친화 크로마토그래피로 정제됨. PBS와 trehalose로 보존된 동결건조 형태로 제공.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.1 µg/mL |
| Neutralization (Neu) | 2–8 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Cat |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | E. coli-derived recombinant feline IL-4 (Gln24–His133) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 5% trehalose |
| Contains | No Preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2608510 |
Product Specific Information
- In direct ELISAs, approximately 15% cross-reactivity is observed with recombinant canine, cotton rat, human, mouse, porcine, and rat IL-4.
- Reconstitute at 0.2 mg/mL in sterile PBS.
- Endotoxin level: <0.10 EU per 1 µg of antibody (LAL method).
Target Information
Interleukin-4 (IL-4) is a pleiotropic, immune-modulatory cytokine produced by activated T cells and serves as a ligand for the interleukin 4 receptor. IL-4 has a broad range of biological actions and shares overlapping functions with IL-13 through receptor binding. STAT6 acts as a key transcription factor mediating IL-4 signaling. The IL-4 gene resides on chromosome 5q within a cytokine gene cluster that includes IL-3, IL-5, IL-13, and CSF2. IL-4, IL-13, and IL-5 are co-regulated by long-range chromosomal elements spanning approximately 120 kilobases. IL-4 delta 2 is a known splice variant of IL-4.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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