Thermo Fisher Scientific CRSP130 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 890-1110 of human MED23 (NP_0012574501) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:CRSP130,uniProtId:Q9ULK4-1,ncbiNodeId:9606,antigenRange:890-1110,antigenLength:1368,antigenImageFileName:PA5-87691_CRSP130_Q9ULK4-1_Rabbit.svg,antigenImageFileNamePDP:PA5-87691_CRSP130_Q9ULK4-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

3.76 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2804348

Product Specific Information

Immunogen sequence: LLKPNDFRNR VSDFVKENSP EHWLQNDWHT KHMNYHKKYP EKLYFEGLAE QVDPPVQIQS PYLPIYFGNV CLRFLPVFDI VIHRFLELLP VSKSLETLLD HLGGLYKFHD RPVTYLYNTL HYYEMHLRDR AFLKRKLVHA IIGSLKDNRP QGWCLSDTYL KCAMNAREEN PWVPDDTYYC RLIGRLVDTM AGKSPGPFPN CDWRFNEFPN PAAHALHVTC V; Positive Samples: Mouse brain, Rat brain; Cellular Location: Nucleus

Target Information

CRSP is ubiquitously expressed in various tissues and functions as a multimeric complex that consists of nine distinct subunits. Several members of the CRSP family share sequence similarity with multiple components of the yeast transcriptional mediator proteins, including CRSP150, which is related to yeast Rgr1, and CRSP70, which is similar to the elongation factor TFIIS. CRSP77 and CRSP150 are also related to proteins within the putative murine mediator complex, while CRSP130 and CRSP34 are largely unrelated to either murine or yeast proteins. CRSP subunits also associate with larger multimeric co-activator complexes, including ARC/DRI, which binds directly to SREBP and nuclear hormone receptors to facilitate transcription, and with NAT, a polymerase II-interacting complex that represses activated transcription.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.