Thermo Fisher Scientific Lambda Light Chain (B-Cell Marker) Monoclonal Antibody (ICO-106)
인간 Lambda 경쇄를 인식하는 B세포 마커 단클론 항체. ELISA에 적합하며, 단백질 A/G로 정제된 액상 형태. 보존제 무첨가 PBS(pH 7.4) 저장용액. 연구용으로만 사용 가능.
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Applications
- ELISA (ELISA): 1–5 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | ICO-106 |
| Immunogen | Purified human IgG (Lambda light chain, UniProt ID: P0CG04-1, antigen range: 1–106) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Target Information
Immunoglobulin classes share a basic four-polypeptide chain structure composed of two heavy chains and two light chains (kappa and lambda, ~22.5 kDa each). Kappa and lambda chains have variable and constant regions that differ antigenically. The typical kappa to lambda ratio is approximately 70:30.
Antibodies against the kappa or lambda light chains are useful for identifying leukemias, plasmacytomas, and certain non-Hodgkin’s lymphomas. Demonstration of clonality in lymphoid infiltrates indicates a malignant clonal proliferation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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