Thermo Fisher Scientific ICAM3 Monoclonal Antibody (OTI1C2), TrueMAB
인간 ICAM3 단백질을 인식하는 마우스 단클론 항체로 Western blot, IHC, ICC/IF에 적합. 동결건조 형태로 제공되며, PBS(8% trehalose) 완충액에 보관. 고순도 친화 크로마토그래피 정제 제품. 연구용으로만 사용 가능.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:400–1:4,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
| Immunocytochemistry (ICC/IF) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1C2 |
| Immunogen | Full length human recombinant protein of human ICAM3 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
CD50 (intracellular adhesion molecule 3, ICAM-3) is a transmembrane glycoprotein expressed by leukocytes. It acts as a counter-receptor for the LFA-1 integrin, mediating interactions between T cells and antigen-presenting cells. ICAM-3 regulates LFA-1 affinity for ICAM-1, promoting T cell activation and proliferation. It plays a key role in initiating immune responses and interacts with CD209 (DC-SIGN), facilitating communication between dendritic cells and granulocytes.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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