Thermo Fisher Scientific ICAM3 Monoclonal Antibody (OTI3A7), TrueMAB

Applications

• Western Blot (WB): 1:400–1:2,000

Product Specifications

Product Specific Information

For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL (Product #89882).

Target Information

CD50 (ICAM-3, intracellular adhesion molecule 3) is a transmembrane glycoprotein expressed on leukocytes and acts as a counter-receptor for LFA-1 integrin. It mediates adhesion between T cells and antigen-presenting cells, regulates LFA-1 affinity for ICAM-1, and induces T cell activation and proliferation.
ICAM-3 is essential in initiating immune responses and interacts with CD209 (DC-SIGN), a C-type lectin on dendritic cells and macrophages, facilitating communication between dendritic cells and granulocytes.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.