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Thermo Fisher Scientific CDK7 Monoclonal Antibody (45H1)
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CDK7 단백질을 인식하는 Mouse Monoclonal Antibody (Clone 45H1). Western blot, ELISA, Immunoprecipitation에 사용 가능. HeLa 세포에서 양성 대조군으로 추천. 연구용으로만 사용.
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마지막 업데이트 2025. 07. 03. 오후 07:12
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Thermo Fisher Scientific MA517210 CDK7 Monoclonal Antibody (45H1) 100 ul pk판매 단위 pk ·
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Thermo Fisher Scientific · Thermo Fisher Scientific CDK7 Monoclonal Antibody (45H1)
Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.2 - 0.4 µg/mL |
| ELISA (ELISA) | Assay-dependent |
| Immunoprecipitation (IP) | 2 µg |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Mouse / IgG2b, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 45H1 |
| Immunogen | Recombinant human protein purified from E. coli (His/ABD-CDK7 136-346 a.a.) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2538678 |
Product Specific Information
A suggested positive control for this product is HeLa cells.
Target Information
The trimeric complex of CDK7, cyclin H and MNAT1 functions as a Cdk-activating kinase (CAK). It is an essential component of the transcription factor TFIIH, involved in transcription initiation and DNA repair. This complex links transcription regulation and the cell cycle. The bound complex contributes to normal double-strand break repair involving BRCA1. CDK7 may be a target of germline cancer-inducing mutations.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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