Thermo Fisher Scientific H4K8ac Polyclonal Antibody
Rabbit polyclonal antibody recognizing acetylated lysine 8 on histone H4. Validated for WB, ICC/IF, and peptide array applications. Supplied as liquid, unconjugated form at 0.5 mg/mL. Suitable for research use only; cross-reactive across species.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunocytochemistry (ICC/IF) | 1 µg/mL |
| Peptide Array (Array) | 0.25 µg/mL |
Product Specifications
| Property | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Acetylated peptide (Lys8) corresponding to Human H4 (aa 6–13) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2532808 |
Product Specific Information
These polyclonal antibodies are of rabbit origin and developed by immunizing animals with specific proteins or peptides. The antibody is affinity purified from rabbit sera and tested for functionality in various research applications.
This product is intended for Research Use Only and is non-hazardous and non-infectious.
Because the antigen sequence is conserved across species, the antibody may show cross-reactivity with other species.
Target Information
Histones are basic nuclear proteins responsible for the nucleosome structure of chromosomal fiber in eukaryotes. Two molecules of each core histone (H2A, H2B, H3, and H4) form an octamer around which approximately 146 bp of DNA is wrapped to form nucleosomes.
The linker histone H1 interacts with linker DNA between nucleosomes and contributes to chromatin compaction.
The H4 gene is intronless and encodes a member of the histone H4 family. Transcripts lack polyA tails and contain a palindromic termination element. This gene resides in the large histone gene cluster on chromosome 6.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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