Thermo Fisher Scientific CYB5R3 Polyclonal Antibody
Thermo Fisher Scientific CYB5R3 Polyclonal Antibody는 인간, 마우스, 랫트에 반응하는 rabbit IgG 항체로, Western blot 및 IHC(P) 분석에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, 1 mg/mL 농도의 액상 형태로 제공됩니다. CYB5R3 단백질(34 kDa)을 검출하며 높은 순도(>95%)를 보장합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
- Publications: View 1 publication
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
- Publications: View publications
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 141–190 of human CYB5R3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2553549 |
Product Specific Information
- Detects endogenous CYB5R3 protein at a molecular weight of 34 kDa.
- Purity is >95% by SDS-PAGE.
Target Information
CYB5R3 (NADH-cytochrome b5 reductase 3, diaphorase 1) is a 301 amino acid protein encoded by the human gene CYB5R3. It belongs to the flavoprotein pyridine nucleotide cytochrome reductase family and has two naturally occurring isoforms:
- Isoform 1: Anchored to the cytoplasmic side of the endoplasmic reticulum and mitochondrion outer membrane.
- Isoform 2: Soluble form found in erythrocytes.
CYB5R3 is involved in fatty acid desaturation and elongation, cholesterol biosynthesis, drug metabolism, and methemoglobin reduction in erythrocytes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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