Thermo Fisher Scientific GCP5 Polyclonal Antibody
Rabbit polyclonal antibody against human GCP5 protein. Validated for WB and IHC applications. Detects endogenous 118 kDa protein with >95% purity. Supplied as liquid, unconjugated, and suitable for research use only.
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Applications
- Western Blot (WB): 1:500–1:1,000
- Immunohistochemistry (Paraffin) (IHC (P)): 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 746–794 of human GCP5 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2553543 |
Product Specific Information
This antibody detects endogenous GCP5 protein at a molecular weight of approximately 118 kDa.
Purity is >95% as determined by SDS-PAGE.
Target Information
The gamma-Tubulin complex is composed of gamma Tubulin and associated proteins GCP2–GCP6, which are essential components of microtubule organizing centers. These components localize to the centrosome and the cytoplasm, contributing to microtubule nucleation and organization.
GCP5 (gamma-Tubulin complex component 5, also known as TUBGCP5) is a 1,024 amino acid protein highly expressed in heart and skeletal muscle.
Defects in GCP5 are implicated in Prader-Willi syndrome (PWS), a rare genetic disorder associated with obesity, compulsive behavior, and lower intellectual ability.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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