Thermo Fisher Scientific Calmodulin 1/2/3 Polyclonal Antibody
Calmodulin 1/2/3 단백질을 인식하는 Rabbit Polyclonal 항체로 WB, IHC, ICC 등 다양한 응용 가능. 인간, 마우스, 랫트 반응성. 고순도 Affinity chromatography 정제, -20°C 보관. 연구용 전용.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human CALM1 (Accession P0DP23), corresponding to amino acid residues V56–L106 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2853575 |
Product Specific Information
Antibody detects endogenous levels of total Calmodulin 1/2/3.
Target Information
Calmodulin is a small, highly conserved calcium-binding protein found in all eukaryotic cells. It can bind up to four calcium ions and acts as an important intracellular receptor for regulatory calcium signals. Upon calcium binding, calmodulin undergoes conformational changes that increase its affinity for target proteins. It functions both directly, by interacting with key target enzymes, and indirectly, via specific kinases. Calmodulin is involved in the regulation of various biological processes including energy metabolism, biosynthesis, cell motility, exocytosis, cytoskeletal assembly, and intracellular modulation of cAMP and calcium concentrations.
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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