Thermo Fisher Scientific IFNA2 Monoclonal Antibody (1D3)

Applications

• ELISA (ELISA)
  Tested Dilution: 10 µg/mL

Product Specifications

Product Specific Information

Sequence of this protein is as follows:
MDLPQTHSLG SRRTLMLLAQ MRRISLFSCL KDRHDFGFPQ EEFGNQFQKA ETIPVLHEMI QQIFNLFSTK DSSAAWDETL LDKFYTELYQ QLNDLEACVI QGVGVTETPL MKEDSILAVR KYFQRITLYL KEKKYSPCAW EVVRAEIMRS FSLSTNLQES LRSKE

Target Information

IFN alpha (Interferon alpha) is a Type I interferon belonging to a family of structurally related, species-specific proteins exclusive to vertebrates. The interaction of IFN-alpha with its receptor components results in activation of signaling pathways involved in innate immune responses against viral infection.
In humans, the gene for IFN alpha is located on chromosome 9. Type I interferons consist of 14 different alpha isoforms, and single beta, omega, epsilon, and kappa isoforms. Homologous molecules are found in many species, including mammals, birds, reptiles, and fish.
IFN alpha is produced primarily by plasmacytoid dendritic cells and acts as a potent component of the antiviral innate immune response while modulating adaptive immunity.
Diseases associated with IFN alpha dysfunction include Hepatitis C and Hepatitis.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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