Thermo Fisher Scientific IFNA2 Monoclonal Antibody (2B1)
인간 IFNA2 단백질을 인식하는 Mouse monoclonal antibody로, Western blot 및 ELISA에 적합합니다. Affinity chromatography로 정제된 액상 항체이며, 보존제가 포함되지 않습니다. -20°C에서 보관하며, 연구용으로만 사용 가능합니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–5 µg/mL |
| ELISA | 1–5 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 2B1 |
| Immunogen | IFNA2 (NP_000596, 24 a.a.–188 a.a.) partial recombinant protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
MDLPQTHSLG SRRTLMLLAQ MRRISLFSCL KDRHDFGFPQ EEFGNQFQKA ETIPVLHEMI QQIFNLFSTK DSSAAWDETL LDKFYTELYQ QLNDLEACVI QGVGVTETPL MKEDSILAVR KYFQRITLYL KEKKYSPCAW EVVRAEIMRS FSLSTNLQES LRSKE
Target Information
IFN alpha (Interferon alpha) is a Type I interferon belonging to a family of structurally related, species-specific proteins exclusive to vertebrates. The interaction of IFN-alpha with its receptor components results in activation of multiple signaling pathways mainly involved in the innate immune response against viral infection.
In humans, the IFN alpha gene is located on chromosome 9. Type I interferons include 14 alpha isoforms and single beta, omega, epsilon, and kappa isoforms. Homologous molecules are present in many species including rodents, birds, reptiles, and fish.
IFN alpha is primarily produced by plasmacytoid dendritic cells and acts as a potent component of the antiviral innate immune response, also modulating adaptive immunity.
Diseases associated with IFN alpha dysfunction include Hepatitis C and Hepatitis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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