
Thermo Fisher Scientific IFNA1 Polyclonal Antibody, MaxPab
인간 IFNA1 단백질을 인식하는 토끼 폴리클로날 항체로, Western blot에 적합. IFN alpha 관련 연구에 활용 가능. 고순도의 친화 크로마토그래피 정제 제품으로, 액상 형태이며 PBS(pH 7.4)에 보존. 연구용 전용 시약.
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1–5 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | IFNA1 (NP_076918.1, 1 a.a. – approximately 189 a.a.) full-length human protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
MASPFALLMV LVVLSCKSSC SLGCDLPETH SLDNRRTLML LAQMSRISPS SCLMDRHDFG FPQEEFDGNQ FQKAPAISVL HELIQQIFNL FTTKDSSAAW DEDLLDKFCT ELYQQLNDLE ACVMQEERVG ETPLMNADSI LAVKKYFRRI TLYLTEKKYS PCAWEVVRAE IMRSLSLSTN LQERLRRKE
Target Information
IFN alpha (Interferon alpha) is a Type I interferon belonging to a family of structurally related, species-specific proteins exclusive to vertebrates.
The interaction of IFN-alpha with its receptor component results in the activation of multiple signaling pathways primarily involved in innate immune responses against viral infection.
In humans, the IFN alpha gene is located on chromosome 9. Type I interferons consist of 14 different alpha isoforms and single beta, omega, epsilon, and kappa isoforms. Homologous molecules are found in many species including rats, mice, birds, reptiles, and fish.
IFN alpha is mainly produced by plasmacytoid dendritic cells and plays a key role in antiviral innate immunity and modulation of adaptive immunity.
Diseases associated with IFN alpha dysfunction include Hepatitis C and Hepatitis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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