Thermo Fisher Scientific C/EBP alpha Polyclonal Antibody
C/EBP alpha 단백질을 검출하는 Thermo Fisher Scientific의 폴리클로날 항체. 마우스 및 랫트 시료에 반응하며 Western blot, IP, ChIP 등에 사용 가능. Protein A로 정제된 1 mg/mL 액상 형태로, -20°C에서 보관. 연구용으로만 사용.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 2 µg/mL | View 1 publication |
| Immunoprecipitation (IP) | Assay-dependent | View 1 publication |
| ChIP assay (ChIP) | - | View 1 publication |
| Miscellaneous PubMed (Misc) | - | View 1 publication |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Mouse, Rat |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant rat C/EBP alpha |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS with 1 mg/mL BSA |
| Contains | 0.01% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2078043 |
Product Specific Information
PA1-825 detects C/EBP alpha protein in mouse samples.
It has been successfully used in Western blot and immunoprecipitation procedures.
By Western blot, this antibody detects 30 and 43 kDa proteins representing C/EBP alpha in mouse 3T3-L1 cells.
These polypeptides are derived from alternative translation initiation.
Target Information
The C/EBP (CCAAT/enhancer binding protein) family of transcription factors—alpha, beta, delta, and epsilon—are widely expressed in various tissues.
These domains contain an evolutionarily conserved five-amino acid motif (the regulatory domain motif RDM) conforming to the consensus sequence (I/V/L) KXEP.
C/EBP transcription factors play a key role in metabolic regulation in liver and fat cells and act in a cascade aiding adipose cell development.
Three C/EBP beta isoforms (LAP*, LAP, and LIP) arise from different translation initiation sites and display distinct gene regulatory functions.
In neurological contexts, C/EBPs are implicated in nerve growth factor mediation, synaptic plasticity, and inflammatory responses in Alzheimer's disease patients.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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