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Thermo Fisher Scientific 53BP1 Polyclonal Antibody
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Thermo Fisher Scientific 53BP1 Polyclonal Antibody

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53BP1 단백질을 인식하는 Rabbit Polyclonal Antibody로 다양한 종에서 반응. Western blot, IHC, ICC/IF 등 여러 응용에 사용 가능. DNA 손상 반응 및 종양 억제 연구에 적합. 항원 친화 크로마토그래피로 정제된 고품질 시약.

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Thermo Fisher Scientific PA116565 53BP1 Polyclonal Antibody 100 ul pk판매 단위 pk
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Thermo Fisher Scientific · Thermo Fisher Scientific 53BP1 Polyclonal Antibody

Thermo Fisher Scientific 53BP1 Polyclonal Antibody

Applications and Tested Dilution

Application Tested Dilution Publications
Western Blot (WB) 1–2 µg/mL -
Immunohistochemistry (Paraffin) (IHC-P) 1:1,000–1:5,000 -
Immunohistochemistry (Frozen) (IHC-F) Assay-Dependent -
Immunocytochemistry (ICC/IF) 1:1,000–1:5,000 3 publications
Flow Cytometry (Flow) 1.5 µg/mL -
Immunoprecipitation (IP) Assay-Dependent -
ChIP assay (ChIP) Assay-Dependent -

Product Specifications

Specification Description
Species Reactivity Bat, Bovine, Dog, Fish, Goat, Human, Mouse, Non-human primate, Rat
Published Species Human
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen Epitope between residues 350–400 of human tumor protein p53 binding protein 1 (NP_005648.1, GeneID 7158)
Conjugate Unconjugated
Form Liquid
Concentration 1 mg/mL
Purification Antigen affinity chromatography
Storage Buffer PBS
Contains 0.02% sodium azide
Storage Conditions -20°C
Shipping Conditions Ambient (domestic); Wet ice (international)
RRID AB_568422

Product Specific Information

  • Human tested in WB, IHC-P, and ICC/IF
  • Mouse and goat tested only in ICC/IF
  • Suggested positive controls: U205, 293T, MO59K cell lysates, and MEF lysates

Target Information

53BP1 (P53-binding protein 1) plays a critical role in tumor suppression and acts as a substrate of ATM kinase. Upon DNA damage, 53BP1 is phosphorylated and localizes to double-strand break sites. It contributes to checkpoint signaling during mitosis, enhances TP53-mediated transcriptional activation, and maintains genomic stability through DNA repair.


For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.


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