Thermo Fisher Scientific RIPK3 Monoclonal Antibody (OTI2H8), TrueMAB
인간 RIPK3 단백질을 인식하는 단클론 항체로 Western blot에 최적화되어 있습니다. 동결건조 형태이며 보존제가 포함되지 않습니다. TrueMAB 형식으로 높은 특이성과 재현성을 제공합니다. 연구용으로만 사용 가능합니다.
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Thermo Fisher Scientific RIPK3 Monoclonal Antibody (OTI2H8), TrueMAB
Applications
- Western Blot (WB)
Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2H8 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 233–518 of human RIPK3 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
RIPK3 is a member of the receptor-interacting protein (RIP) family of serine/threonine kinases, containing a unique C-terminal domain. It localizes primarily in the cytoplasm and mitochondria, and participates in TNF receptor-I signaling. RIPK3 can induce apoptosis and weakly activate NF-κB. Caspase-8 prevents RIPK3-dependent necrosis by forming a proteolytically active complex with CFLAR, which is essential for its protective function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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