Thermo Fisher Scientific CD279 (PD-1) Recombinant Rabbit Monoclonal Antibody (SJ01-91)
Thermo Fisher의 CD279 (PD-1) 재조합 토끼 단클론 항체(SJ01-91)는 인간 PD-1 단백질을 인식합니다. Western blot과 IHC(파라핀 절편)에 적합하며, 높은 특이성과 재현성을 제공합니다. 단백질 A 정제, 1 mg/mL 농도, 장기 보관 시 -20°C 권장.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | SJ01-91 |
| Immunogen | Synthetic peptide within Human PD-1 (aa 1–50) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | TBS, pH 7.4, with 40% Glycerol, 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term; for long term, store at -20°C (avoid freeze/thaw cycles) |
| Shipping Conditions | Wet ice |
| RRID | AB_2809366 |
Product Specific Information
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The antibody DNA sequences from immunoreactive rabbits are cloned and expressed in HEK293 cells. Individual clones are screened to select the best candidates for production.
Advantages:
- High specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulation
- Broad immunoreactivity due to the large rabbit immune repertoire
Target Information
PD-1 (Programmed Cell Death Protein 1, CD279) is an inhibitory receptor expressed on activated T cells. It binds to its ligands PD-L1 and PD-L2 on antigen-presenting cells to downregulate immune responses, preventing overactivation and autoimmunity. PD-1 is involved in maintaining immune tolerance and is a key target in immuno-oncology research. Although its predicted molecular weight is known, PD-1 often migrates at a higher molecular weight in SDS-PAGE.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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