Thermo Fisher Scientific CD8b Monoclonal Antibody (PPT23), PE
돼지 CD8β 항원을 인식하는 단클론 항체로, PE 형광체가 결합되어 유세포분석(Flow Cytometry)에 적합합니다. 단백질 A로 정제되었으며, 동결건조 형태로 제공됩니다. 4°C에서 암소 보관하며, 재구성 후 사용 가능합니다.
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Applications
- Flow Cytometry (Flow): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Pig |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | PPT23 |
| Immunogen | Porcine thymus membrane lysate |
| Conjugate | PE (R-Phycoerythrin) |
| Excitation / Emission Max | 565 / 576 nm |
| Form | Lyophilized |
| Purification | Protein A |
| Storage Buffer | PBS with 5% sucrose, 1% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C, store in dark, DO NOT FREEZE |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2745403 |
Additional Formats
Product Specific Information
This antibody recognizes a different epitope on the CD8 beta chain compared to clone PPT22.
Reconstitute with 1 mL distilled water before use.
Target Information
The CD8B antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes. It mediates efficient cell-cell interactions within the immune system. Acting as a coreceptor, the CD8 antigen and the T-cell receptor recognize antigens presented by antigen-presenting cells (APCs) in the context of class I MHC molecules.
The functional coreceptor can be a homodimer (two alpha chains) or a heterodimer (one alpha and one beta chain). Both chains share homology with immunoglobulin variable light chains. This gene encodes CD8 beta chain isoforms, with multiple alternatively spliced transcript variants producing distinct membrane-associated or secreted forms. A pseudogene on chromosome 2 has also been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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