Thermo Fisher Scientific SRF Polyclonal Antibody
Rabbit polyclonal antibody targeting human Serum Response Factor (SRF). Validated for WB, IHC, IHC-P, and IP applications. Supplied as unconjugated liquid form at 1 mg/mL concentration. Recommended storage at 4°C with 1-year shelf life.
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Thermo Fisher Scientific SRF Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunohistochemistry (IHC) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:500–1:2,000 |
| Immunoprecipitation (IP) | 2–10 µg/mg lysate |
Product Specifications
| Specification | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 458 and 508 of Human Serum Response Factor (SRF). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Application Note: For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
Target Information
Serum Response Factor (SRF) is a transcription factor that binds the serum response element (SRE), mediating transient gene responses to growth stimulation.
SRF-binding sites act as constitutive promoter elements in many muscle-specific promoters.
SRF is required for cardiac differentiation and maturation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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