Thermo Fisher Scientific MCHR1 Polyclonal Antibody
Rabbit polyclonal antibody targeting human MCHR1 for IHC and ELISA applications. Recognizes multiple mammalian species with high identity. Unconjugated, purified by antigen affinity chromatography, supplied as liquid in PBS with sodium azide. Suitable ...
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Applications
Immunohistochemistry (Paraffin) [IHC (P)]
- Tested dilution: 10 µg/mL
ELISA
- Tested dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Bovine, Dog, Human, Non-human primate |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 18 amino acid peptide from C-terminus of human MCHR1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2550378 |
Product Specific Information
Percent identity with other species by BLAST analysis:
Human, Chimpanzee, Gibbon, Monkey, Bovine, Dog, Panda (100%);
Mouse, Rat, Horse, Pig (94%);
Hamster, Elephant (89%).For IHC(P), use heat-induced antigen retrieval in pH 6.0 citrate buffer.
After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen.
Target Information
MCHR1 is a member of the G protein-coupled receptor family 1. It is an integral plasma membrane protein which binds melanin-concentrating hormone. The encoded protein can inhibit cAMP accumulation and stimulate intracellular calcium flux, and is probably involved in the neuronal regulation of food consumption. Although structurally similar to somatostatin receptors, this protein does not seem to bind somatostatin.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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