Thermo Fisher Scientific Human BACE2 Synthetic Peptide
Human BACE2 단백질의 16개 아미노산 서열 기반 합성 펩타이드입니다. BACE2 관련 항체의 블로킹 실험에 사용 가능합니다. Alzheimer 연구 등 APP 절단 기전 분석에 유용합니다. 순도 높은 액상 형태로 제공되며 -20°C에서 보관합니다.
- 카탈로그번호
- PEP0076
- 카테고리
- Protein
- 판매단위
- pk
카탈로그
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Thermo Fisher Scientific Human BACE2 Synthetic Peptide
Applications
- Control (Ctrl): Assay-dependent
- Blocking Assay (BLOCK): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
Product Specific Information
This peptide corresponds to 16 amino acids near the carboxy terminus of human BACE2.
PEP-0076 can be used as a blocking peptide with polyclonal antibody PA5-19951.
Target Information
BACE2 (Beta Secretase 2) is responsible for the proteolytic processing of the amyloid precursor protein (APP).
BACE2 cleaves APP between residues 690 and 691, resulting in the generation and extracellular release of beta-cleaved soluble APP.
It is also known to cleave APP between residues 671 and 672.
Accumulation of APP is a hallmark of Alzheimer’s disease and a frequent complication in adult Down syndrome patients.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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