Thermo Fisher Scientific PHF7 Monoclonal Antibody (OTI1C2), TrueMAB
PHF7 단백질을 인식하는 마우스 단클론 항체로, Western blot에 최적화되어 있습니다. 동결건조 형태로 제공되며, 재구성 후 약 1 mg/mL 농도로 사용 가능합니다. 인간 시료에 반응하며, 보존제 없이 PBS와 트레할로오스로 안정화되어 있습니다.
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Applications
- Western Blot (WB): Tested dilution 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1C2 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 155–381 of human PHF7 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882) to ensure carrier-free conditions.
Target Information
Spermatogenesis is regulated by extracellular and intracellular factors as well as interactions among testicular interstitial cells, Sertoli cells, and germ cells.
This gene is expressed in Sertoli cells but not in germ cells. Lack of expression has been observed in patients with spermatogenic arrest at the spermatocyte stage, which can lead to oligospermia or azoospermia.
The encoded proteins contain plant homeodomain (PHD) finger domains, also known as leukemia-associated protein (LAP) domains, involved in transcriptional regulation.
The PHF7 protein localizes to the nucleus and may play a role in transcriptional regulation during spermatogenesis. Two isoforms are produced from transcript variants of this gene.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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