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ELK Biotechnology cPLA2-ε rabbit pAb
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ELK Biotechnology cPLA2-ε rabbit pAb

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인간 PLA2G4E 유래 합성 펩타이드로 제작된 토끼 다클론 항체로, IHC, IF, ELISA에 사용 가능. 세포질 및 세포막에 위치한 cPLA2-ε 단백질 검출에 적합하며, 1mg/ml 농도로 제공되고 -20°C에서 1년 보관 가능.

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pk
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ELK Biotechnology ES4712-100UL cPLA2-ε rabbit pAb, 100UL pk판매 단위 pk ·
재고 확인 필요
402,000원VAT 포함 442,200원
ELK Biotechnology ES4712-50UL cPLA2-ε rabbit pAb, 50UL pk판매 단위 pk ·
재고 확인 필요
301,000원VAT 포함 331,100원

ELK Biotechnology · ELK Biotechnology cPLA2-ε rabbit pAb

ELK Biotechnology cPLA2-ε rabbit pAb

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항목 내용
Product name cPLA2-ε rabbit pAb
Alternative Names PLA2G4E; Cytosolic phospholipase A2 epsilon; cPLA2-epsilon; Phospholipase A2 group IVE
Applications IHC; IF; ELISA
Recommended Dilutions Immunohistochemistry: 1/100 - 1/300
ELISA: 1/40000
Not yet tested in other applications
Immunogen Antiserum produced against synthesized peptide derived from human PLA2G4E (AA range: 401–450)
Host Rabbit
Storage -20°C / 1 year
Clonality Polyclonal
Isotype IgG
Concentration 1 mg/ml
GeneID (Human) 123745
Human Swiss-Prot No Q3MJ16
Cellular Localization Cytoplasm, cytosol; Early endosome membrane; Peripheral membrane protein (cytoplasmic side); Lysosome membrane; Cell membrane; Targeted to clathrin-independent endocytotic vesicles through binding to phosphoinositides, especially phosphatidylinositol 4,5-bisphosphates.
Species Reactivity Human; Rat; Mouse

Background

  • Catalytic activity: Phosphatidylcholine + H₂O → 1-acylglycerophosphocholine + a carboxylate
  • Domain: N-terminal C2 domain associates with lipid membranes and mediates regulation by presenting the active site in response to cytosolic Ca²⁺
  • Enzyme regulation: Stimulated by cytosolic Ca²⁺
  • Function: Calcium-dependent phospholipase A2 that hydrolyzes glycerophospholipids at the sn-2 position
  • Similarity: Contains 1 C2 domain and 1 PLA2c domain
  • Subcellular location: Translocates to lysosomal membranes in a calcium-dependent fashion

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