ELK Biotechnology Cystatin 8 rabbit pAb
Cystatin 8 rabbit pAb는 인간 및 생쥐 시료에서 반응하는 다클론 항체로, IHC, IF, ELISA에 적합합니다. 인간 CST8 유래 합성 펩타이드로 면역화되었으며, 생식 관련 단백질 연구에 유용합니다. -20°C에서 1년 보관 가능합니다.
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제품명
Cystatin 8 rabbit pAb
기본 정보
| 항목 | 내용 |
|---|---|
| Alternative Names | CST8; CRES; Cystatin-8; Cystatin-related epididymal spermatogenic protein |
| Applications | IHC; IF; ELISA |
| Recommended Dilutions | Immunohistochemistry: 1/100 - 1/300 ELISA: 1/40000 Not yet tested in other applications |
| Immunogen | Synthesized peptide derived from human CST8 (AA range: 31–80) |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| GeneID (Human) | 10047 |
| Human Swiss-Prot No | O60676 |
| Cellular Localization | Secreted |
| Species Reactivity | Human; Mouse |
| Storage | -20°C / 1 year |
| Host | Rabbit |
배경 정보
The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity.
There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins, and the kininogens.
The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions.
The cystatin locus on chromosome 20 contains the majority of the type 2 cystatin genes and pseudogenes.
This gene is located in the cystatin locus and encodes a protein similar to type 2 cystatins. The encoded protein exhibits highly tissue-specific expression in the reproductive tract, suggesting implicit roles in reproduction.
Alternative splicing results in multiple transcript variants.
[provided by RefSeq, Aug 2013]
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