ELK Biotechnology SOD-2 rabbit pAb
SOD-2 rabbit pAb는 미토콘드리아 내 Superoxide Dismutase 2 단백질을 인식하는 토끼 폴리클로날 항체입니다. WB, IHC, IF, ELISA에 사용 가능하며, 인간, 마우스, 랫트 시료에 반응합니다. 산화 스트레스 연구 및 미토콘드리아 기능 분석에 적합합니다.
- 카탈로그번호
- ES4305-xxxxx (2개 옵션)
- 판매단위
- pk
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제품명
SOD-2 rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Alternative Names | SOD2; Superoxide dismutase [Mn], mitochondrial |
| Applications | WB; IHC; IF; ELISA |
| Recommended Dilutions | IHC-p: 1/100–1/300; Western Blot: 1/500–1/2000; ELISA: 1/10000; Not yet tested in other applications |
| Immunogen | The antiserum was produced against synthesized peptide derived from the internal region of human SOD2 (AA range: 91–140) |
| Host | Rabbit |
| Storage | -20°C for 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 24 kDa |
| Gene ID (Human) | 6648 |
| Human Swiss-Prot No. | P04179 |
| Cellular Localization | Mitochondrion matrix |
| Species Reactivity | Human; Mouse; Rat |
Background
This gene is a member of the iron/manganese superoxide dismutase family. It encodes a mitochondrial protein that forms a homotetramer and binds one manganese ion per subunit. This protein binds to the superoxide byproducts of oxidative phosphorylation and converts them to hydrogen peroxide and diatomic oxygen. Mutations in this gene have been associated with idiopathic cardiomyopathy (IDC), premature aging, sporadic motor neuron disease, and cancer. Alternative splicing of this gene results in multiple transcript variants. A related pseudogene has been identified on chromosome 1. (Provided by RefSeq, Apr 2016)
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